Redox regulation of Smac mimetic-induced cell death
نویسنده
چکیده
Cell death and survival programs are controlled by the cellular redox state, which is typically dysregulated during oncogenesis. A recent study reports that the inhibition of antioxidant defenses resulting from glutathione depletion can prime acute lymphoblastic leukemia cells for death induced by Smac mimetics.
منابع مشابه
RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2015